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Congratulations to Evi Stavrou, MD (Co-PI with Anirban Sen Gupta, PhD) on receiving a Case-Coulter Translational Research Partnership (CCTRP) award titled NeutroStat: neutrophil-targeted nanomedicine for treating venous thromboembolism (VTE). This aim of this 1-year, $100K is to test NeutroStat, a nanomedicine technology that targets neutrophil-platelet complexes at the site of growing venous thrombi for site-specific delivery of therapeutic molecules to reduce neutrophil extracellular trap formation. Currently, venous thrombi are treated by downstream anticoagulant therapies that are associated with systemic bleeding risks in many patients. NeutroStat promises to reduce the upstream mechanisms that drive coagulation and thrombus formation, in a highly targeted fashion, that will significantly improve therapeutic safety and efficacy in the treatment of venous thromboembolism.
This article was originally posted by the Daily.
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